Description This is an over the counter product - it does not require prescription.LubriSynâ„¢ is an odorless, tasteless, colorless oral gel with hyaluronic acid as its main component. Hyaluronic acid is a naturally occurring part of tissues and is a primary constituent of synovial fluid, the viscous substance that lubricates joints and allows two adjacent cartilage caps to glide upon one another with minimal friction. Daily use of LubriSyn avoids the peaks and valleys associated with HA injections by maintaining a consistent bio-available serum level. An oral product is also less invasive to the animal, safer to administer and more easily transported. Intra-articular injections carry risks of synovial "flare," or pain near the injection site, and the possible degradation of healthy performance. LubriSyn provides a consistent, stable and proven supplement that can be administered with none of the risks or side effects prevalent with injection products. When HA is given orally, there are no side effects. As a naturally occurring substance, LubriSyn will not show up in post-competition testing. Chemistry: Sodium hyaluronate, hyaluronic acid, hyaluronan and HA are terms for the same glycosaminoglycan that can exist in different forms depending on their chemical environment. This glycosaminoglycan is composed of repeating subunits of D-Glucuronic acid and N-Acetyl-D-Glucosamine connected with glycosidic bonds. Because LubriSyn (sodium hyaluronate) is extracted from a microbial source, it is free of dermatan, chondroitin sulfate and other glycosaminoglycan contamination. Pharmacology: HA is highly bio-compatible and bio-degradable. It regulates normal cellular constituents, decreasing the impact of exudation, enzyme release and subsequent degradation of joint integrity. Directions Complete results appear within 1-2 weeks of consistent use. Daily Maintenance Load: Administer 15 ml once daily. Initial Load Period: LubriSyn may be administered at double (30 ml) the daily maintenance level for an initial loading period of five days or more. Horses with joint health issues may benefit from an extended initial loading period of up to 14 days. Pre-Performance Load: LubriSyn may be administered at double (30 ml) the daily maintenance level for a pre-performance loading period of three days or more. Contraindications: There are no known contraindications for the use of LubriSyn oral gel in horses. Toxicology: LubriSyn was administered at two, three and five times the recommended maintenance dosage of 75 mg daily for 90 days with no adverse effects upon hematology or clinical chemistry parameters observed. Side Effects: There have been no local or systemic side effects observed in the field trials. Manufacturer: Halstrum, LLC - LubriSyn
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