--- product_id: 284788688 title: "Advantage Spot On Flea Treatment, 4 Pack, Extra Large Dogs 25-40kg, 400mg" brand: "advantage" price: "$79.09" currency: USD in_stock: true category: "Advantage" url: https://www.desertcart.ec/products/284788688-advantage-spot-on-flea-treatment-4-pack-extra-large-dogs store_origin: EC region: Ecuador --- # Easy pipette application Kills fleas in 24h Protects up to 4 weeks Advantage Spot On Flea Treatment, 4 Pack, Extra Large Dogs 25-40kg, 400mg **Brand:** advantage **Price:** $79.09 **Availability:** ✅ In Stock ## Summary > 🦴 Stay ahead of fleas—because your big dog deserves big protection! ## Quick Answers - **What is this?** Advantage Spot On Flea Treatment, 4 Pack, Extra Large Dogs 25-40kg, 400mg by advantage - **How much does it cost?** $79.09 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.ec](https://www.desertcart.ec/products/284788688-advantage-spot-on-flea-treatment-4-pack-extra-large-dogs) ## Best For - advantage enthusiasts ## Why This Product - Trusted advantage brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Safe & Non-Invasive:** Works on contact without bloodstream absorption—fleas die before they bite. - • **Long-Lasting Defense:** One application protects your pet and home from reinfestation for a full month. - • **Home & Pet Protection:** Clinically proven to kill fleas on your dog and disrupt the flea life cycle in your environment. - • **Rapid Flea Eradication:** Eliminate fleas within 24 hours to keep your dog itch-free and happy. - • **Targeted Spot-On Formula:** Precision pipette design ensures quick absorption and even coverage on your dog’s skin. ## Overview Advantage Spot On Flea Treatment for Extra Large Dogs (25-40kg) delivers fast-acting, clinically proven flea control that kills fleas within 24 hours and prevents reinfestation for up to four weeks. Its easy-to-apply pipette formula spreads quickly across the skin without bloodstream absorption, ensuring fleas die on contact before biting. Trusted by thousands, it protects both your pet and home, breaking the flea life cycle with every monthly application. ## Description Product Description "Help protect your pet and your home from fleas with Advantage 400 mg Spot On Solution For Extra Large Dogs between 25 - 40 kg. Our spot on flea treatment kills fleas and prevents further infestations for up to 4 weeks, as well treating biting lice in dogs. Advantage is a quick and easy-to use pipette formulation. Once applied, the product spreads quickly across your pet’s skin and coat. The product is not absorbed into the bloodstream, meaning that fleas do not have to bite to be killed 1. Advantage also kills flea larvae in the home wherever the treated pet goes. It will kill fleas within 24 hours, and is available without a prescription. Advantage can be reapplied to your dog every 4 weeks to keep them protected against fleas. Advantage Spot On is quick and easy to use: Apply one pipette of Advantage Spot On to the skin between the shoulder blades. With Advantage fleas are dead, not fed. 1. Mehlhorn H Parasitology Research 2001 198 (v1.0) 87:198-207, information is regarding mode of action and is not intended to imply parasites can be completely stopped from biting. Use medicines responsibly. Advantage contains imidacloprid. Legal category: NFA-VPS. Further information is available from the datasheet or on request. Advantage, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. Elanco UK AH Ltd, Form 2, Bartley Wood Business Park, Bartley Way, Hook, RG27 9XA. Copyright 2025 Elanco UK AH Ltd. Date of Preparation: May 2025. PM-UK-25-0253." Directions Apply one pipette directly onto the skin at the back of the dog's neck, between the shoulder blades, and repeat every 4 weeks. ## Features - ADVANTAGE FLEA TREATMENT: Use Spot On Flea Treatment to keep your pets protected from fleas. Advantage spreads quickly across your pet’s skin and coat and is not absorbed into the bloodstream, meaning those pesky parasites do not have to bite to die 1. - FAST-ACTING FLEA PROTECTION: If you suspect your pet might be suffering with fleas, take action. Advantage kills fleas within 24 hours of application, meaning your pet can get back to living a full and happy life. - PREVENT REINFESTATION: For every adult flea that you see, there are many more eggs, larvae and pupae hidden away in carpets, upholstery and bedding. Apply spot on treatment every four weeks to prevent further infestations. - FAST & SIMPLE TO APPLY: Protect your pets from fleas with our easy to apply pipette formulation. Apply one pipette evenly to three to four spots on the top of the back from the shoulder to the base of the tail. - PROTECT YOUR PET, PROTECT YOUR HOME: If your pet has fleas, your home has fleas. Advantage is clinically proven to kill fleas, giving you peace of mind. With Advantage Flea Treatment, fleas are dead, not fed. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00OHPZM98 | | Active Ingredients | Imidacloprid | | Age Range Description | All Life Stages | | Best Sellers Rank | 16 in Pet Supplies ( See Top 100 in Pet Supplies ) 1 in Dog Flea Drops | | Brand Name | Advantage | | Country Of Origin | United Kingdom | | Customer Reviews | 4.6 4.6 out of 5 stars (1,095) | | Dog Breed Size | Large | | Item Form | Drops | | Manufacturer | Elanco | | Manufacturer Part Number | H070658 | | Target Species | Dog | | Unit Count | 4.00 count | ## Product Details - **Active ingredients:** Imidacloprid - **Age range (description):** All Life Stages - **Brand:** Advantage - **Dog Breed Size:** Large - **Item form:** Drops - **Size:** Extra Large Dogs (25-40 kg) - **Unit count:** 4.00 count ## Images ![Advantage Spot On Flea Treatment, 4 Pack, Extra Large Dogs 25-40kg, 400mg - Image 1](https://m.media-amazon.com/images/I/81gFNeUND0L.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: is this item easy to use** A: Yes very easy to use ,my cat had been used to other spot on with little effect .After using Advantage for the first but definitely not the last time after other's online recommendations ,I watched the fleas literally falling off my cat whilst they were dying almost immediately ,I would say very effective **Q: I have a Chihuahua and we live in Egypt six months of the year. Comments about efficacy of this product(Advantage), with ticks would be very welcome** A: Hiya. Live in Cheshire here. We have all sorts of creepy critters that love to attach themselves to my dogs and cats, free meal all round! I researched this product after wasting so much money on frontline, this didn't work for me anymore. I purchased just before Xmas and dropped it on animals, within minutes I spotted a flea trying to hang onto my dog's coat (probably gasping for air, didn't get magnifying glass out!) ;) there have been no fleas, ticks or mites on any of my 7 animals since! :) will be buying again next month to repeat. It's brilliant and really works. **Q: Is it the same ingredients for cats & dogs ?** A: Advantage Spot On Flea Treatment is for treating flea infestations in dogs, cats and rabbits suitable for puppies and kittens 8 weeks and older. Using Advantage Flea Treatment, fleas are killed within one day following treatment. **Q: does this product kill ticks?** A: No it doesn't. I started using this 2 weeks ago. I found a tick on my dog 5 days ago. I recieved my 'tick remover' today and have just removed the tick and it was still alive! I've just drowned the horrid tick in mouthwash, vinegar and bleach! So I would say NO this product does not kill ticks. ## Frequently Bought Together - Advantage Spot On Flea Treatment 400 Extra Large Dogs 25-40kg, 4 pipettes - Bob Martin Clear 3-in-1 Wormer for Dogs (4 Tablets) - For Small, Medium and Large Dogs up to 40kg, Clinically Proven Treatment --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.ec/products/284788688-advantage-spot-on-flea-treatment-4-pack-extra-large-dogs](https://www.desertcart.ec/products/284788688-advantage-spot-on-flea-treatment-4-pack-extra-large-dogs) --- *Product available on Desertcart Ecuador* *Store origin: EC* *Last updated: 2026-10-15*